6 Hair Removal Prescription Oral Medications - 1
- Spironolactone (Aldactone)
- Finasteride (Marketed As Propecia And Proscar)
- Flutamide
- Cyproterone acetate (Not Available In The US)
- Ketoconazole
- Gonadotrophin Releasing Hormone Agonists
Basic Facts
Some prescription oral medications have been found to affect hair growth. They can be helpful in reducing hair growth in some consumers, but it's important to discuss possible side effects with your physician. Drugs that can reduce hair growth.
1. Spironolactone (Aldactone)
Spironolactone (also known as Aldactone) is arguably the number one hirsutism treatment of choice for dermatologists in the US. Spironolactone has antiandrogenic effects that may enhance treatment of several androgen-excess conditions, particularly severe hirsutism.
Spironolactone has several properties that make it suitable for use in treating hirsutism. It interferes with the production of testosterone and it increases the metabolism of any testosterone that is produced. Spironolactone binds to cell androgen receptors and blocks them from binding to naturally produced androgens. In addition with long term spironolactone use, there is a gradual reduction in 5 alpha reductase activity. It is this enzyme that converts testosterone to the more potent, hair follicle stimulating, dihydrotestosterone.
Treatment protocols may involve continuous spironolactone use at 50mg to 200mg per day or cyclic use. For example 50mg or 100mg twice daily from the 4th to the 22nd day of the menstrual cycle. Numerous treatment protocols involving spironolactone have been used in different studies, but no particular treatment approach has been shown to be significantly superior. Combination therapy with an oral contraceptive pill or dexamethasone appears to have an improved beneficial effect on hirsutism and limits side effects.
Spironoolactone is a diuretic, so it's advised to drink plenty of water while taking it. Side effects with spironolactone are generally transient. As with all antiandrogens , spironolactone use should be avoided during pregnancy and in women who have a family history of breast cancer, although there is no proven association between spironolactone and breast malignancy.